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1. (WO2018160043) PREPARATION, COMPRISING INCLUSION COMPLEX OF VARENICLINE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, FOR ORAL ADMINISTRATION

Pub. No.:    WO/2018/160043    International Application No.:    PCT/KR2018/002551
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Sat Mar 03 00:59:59 CET 2018
IPC: A61K 9/00
A61K 47/40
A61K 9/08
A61K 9/16
A61K 31/55
A61K 47/12
Applicants: CTC BIO, INC.
주식회사 씨티씨바이오
Inventors: JEON, Hong Ryeol
전홍렬
KWON, Do-Woo
권도우
LEE, Bong-Sang
이봉상
MEANG, Seul Ki
맹슬기
PARK, Su-Jun
박수준
KWAK, Seong-Shin
곽성신
Title: PREPARATION, COMPRISING INCLUSION COMPLEX OF VARENICLINE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, FOR ORAL ADMINISTRATION
Abstract:
The present invention relates to a pharmaceutical preparation for oral administration, the pharmaceutical preparation comprising an inclusion complex formed by including varenicline or a pharmaceutically acceptable salt thereof in cyclodextrin. The pharmaceutical preparation can improve the convenience of administration by effectively blocking the bitter taste of a drug and the irritation in swallowing a drug, can be expected to have a stabilizing effect in view of oxidation stability of varenicline, and can improve the solubility of a drug.