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1. (WO2018159985) COMPOSITION COMPRISING HEXANE FRACTION OF CLERODENDRUM TRICHOTOMUM EXTRACT OR COMPOUND ISOLATED FROM CLERODENDRUM TRICHOTOMUM EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING SKIN WRINKLE

Pub. No.:    WO/2018/159985    International Application No.:    PCT/KR2018/002406
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Wed Feb 28 00:59:59 CET 2018
IPC: A61K 8/60
A61K 8/97
A23L 33/10
A23L 33/105
A61K 31/7016
A61K 36/855
A61Q 19/08
Applicants: KOREA INSTITUTE OF ORIENTAL MEDICINE
한국 한의학 연구원
Inventors: CHAE, Sung Uk
채성욱
IM, A-Rang
임아랑
Title: COMPOSITION COMPRISING HEXANE FRACTION OF CLERODENDRUM TRICHOTOMUM EXTRACT OR COMPOUND ISOLATED FROM CLERODENDRUM TRICHOTOMUM EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING SKIN WRINKLE
Abstract:
The present invention relates to a cosmetic composition comprising martynoside of Chemical Formula 1 or an acceptable salt thereof; isomartynoside of Chemical Formula 2 or an acceptable salt thereof; or a hexane fraction of a Clerodendrum trichotomum extract as an effective ingredient for preventing or alleviating skin wrinkles. The ingredient suppresses cell damage attributed to UV light and remarkably inhibits the expression of MMP-1 and thus can be applied to a cosmetic product, a health functional food, or a medicinal product for preventing, alleviating or treating skin wrinkles.