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|1. (WO2018159906) STABILIZED EXTERNAL USE AGENT COMPRISING THYMOSIN BETA-4 AS EFFECTIVE INGREDIENT|
|Applicants:||G-TREEBNT CO., LTD.
|Inventors:||CHOI, Jun Won
LEE, Si Young
UM, Tae Heum
|Title:||STABILIZED EXTERNAL USE AGENT COMPRISING THYMOSIN BETA-4 AS EFFECTIVE INGREDIENT|
The present invention relates to a stabilized external use agent comprising thymosin beta-4 as an effective ingredient and, more particularly, to an external use agent having therapeutically effective Tβ4 improved in biological activity and stability. Through the improvement, the external use according to the present invention can maintain the biological activity of Tβ4 and minimize the generation of Tβ4 sulfoxide attributed to an oxidation reaction and the generation of multimers attributed to aggregation, thereby providing Tβ4 in a stable state.