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1. (WO2018159845) PREVENTIVE OR THERAPEUTIC AGENT FOR HTLV-1-ASSOCIATED MYELOPATHY USING LOW-DOSE ANTI-CCR4 ANTIBODY

Pub. No.:    WO/2018/159845    International Application No.:    PCT/JP2018/008166
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Sat Mar 03 00:59:59 CET 2018
IPC: A61K 39/395
A61K 31/52
A61K 31/573
A61K 31/706
A61K 38/13
A61K 45/00
A61P 19/00
A61P 31/12
A61P 35/02
A61P 37/06
A61P 43/00
Applicants: ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE
学校法人 聖マリアンナ医科大学
KYOWA HAKKO KIRIN CO., LTD.
協和発酵キリン株式会社
Inventors: YAMANO Yoshihisa
山野 嘉久
Title: PREVENTIVE OR THERAPEUTIC AGENT FOR HTLV-1-ASSOCIATED MYELOPATHY USING LOW-DOSE ANTI-CCR4 ANTIBODY
Abstract:
The purpose of the present invention is to provide a novel therapeutic or preventive agent for human T-cell leukemia virus-1-associated myelopathy (HAM), characterized by containing an anti-human CC-chemokine receptor 4 (CCR4) antibody or a fragment of the antibody as an active ingredient and by a dosage regimen of said antibody or of a fragment of the antibody. The present invention pertains to a therapeutic or preventative agent for HAM, which is characterized by containing an anti-human CCR4 antibody or a fragment of the antibody as an active ingredient and in that the antibody or fragment of the antibody is administered at a low dose.