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1. (WO2018158985) ALLERGY ANTIGEN AND EPITOPE THEREOF
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Pub. No.: WO/2018/158985 International Application No.: PCT/JP2017/032005
Publication Date: 07.09.2018 International Filing Date: 05.09.2017
IPC:
C07K 14/415 (2006.01) ,A23J 3/16 (2006.01) ,A23L 11/30 (2016.01) ,A61K 39/35 (2006.01) ,A61P 37/08 (2006.01) ,G01N 33/50 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
415
from plants
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
J
PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
3
Working-up of proteins for foodstuffs
14
Vegetable proteins
16
from soybean
[IPC code unknown for A23L 11/30]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
35
Allergens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
08
Antiallergic agents
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
学校法人藤田学園 FUJITA ACADEMY [JP/JP]; 愛知県豊明市沓掛町田楽ヶ窪1番地98 1-98, Dengakugakubo, Kutsukake-cho, Toyoake-shi, Aichi 4701192, JP
ホーユー株式会社 HOYU CO., LTD. [JP/JP]; 愛知県名古屋市東区徳川1丁目501番地 501, Tokugawa 1-chome, Higashi-ku, Nagoya-shi, Aichi 4618650, JP
Inventors:
松永 佳世子 MATSUNAGA, Kayoko; JP
矢上 晶子 YAGAMI, Akiko; JP
下條 尚志 SHIMOJO, Naoshi; JP
大野 史晃 OHNO, Fumiaki; JP
Agent:
小野 新次郎 ONO, Shinjiro; JP
山本 修 YAMAMOTO, Osamu; JP
宮前 徹 MIYAMAE, Toru; JP
中西 基晴 NAKANISHI, Motoharu; JP
廣瀬 しのぶ HIROSE, Shinobu; JP
Priority Data:
PCT/JP2017/00859303.03.2017JP
Title (EN) ALLERGY ANTIGEN AND EPITOPE THEREOF
(FR) ANTIGÈNE D'ALLERGIE ET SON ÉPITOPE
(JA) アレルギーの抗原およびそのエピトープ
Abstract:
(EN) The present invention provides: a novel antigen for an allergy to soybean; a method and a kit for diagnosing an allergy to soybean; a pharmaceutical composition containing the antigen; soybean or a soybean processed product, from each of which the antigen is removed; and a tester for determining the presence or absence of a soybean antigen in a subject. The present invention also relates to: a polypeptide containing an epitope of an allergen; a kit, a composition and a method for diagnosing an allergy, in each of which the polypeptide is contained; a pharmaceutical composition containing the polypeptide; and a food raw material or an edible processed product, in each of which an antigen containing the polypeptide is removed or reduced or the polypeptide is cleaved or removed. The present invention also relates to a tester for determining the presence or absence of an antigen in a subject.
(FR) La présente invention concerne : un nouvel antigène pour une allergie au soja ; un procédé et un kit pour diagnostiquer une allergie au soja ; une composition pharmaceutique contenant l'antigène ; du soja ou un produit traité à base de soja, à partir de chacun desquels l'antigène est éliminé ; et un testeur pour déterminer la présence ou l'absence d'un antigène de soja chez un sujet. La présente invention concerne également : un polypeptide contenant un épitope d'un allergène ; un kit, une composition et un procédé de diagnostic d'une allergie, dans chacun desquels le polypeptide est contenu ; une composition pharmaceutique contenant le polypeptide ; et une matière première alimentaire ou un produit traité comestible, dans chacun desquels un antigène contenant le polypeptide est éliminé ou réduit ou le polypeptide est clivé ou éliminé. La présente invention concerne en outre un testeur pour déterminer la présence ou l'absence d'un antigène chez un sujet.
(JA) 本発明は、大豆に対するアレルギーの新規抗原、大豆に対するアレルギーの診断方法および診断キット、当該抗原を含む医薬組成物、当該抗原が除去された大豆または大豆加工品、ならびに対象物における大豆抗原の有無を判定するためのテスターを提供する。 本発明はまた、アレルゲンのエピトープを含むポリペプチド、当該ポリペプチドを含むアレルギーの診断キット、診断用組成物、及び診断方法、当該ポリペプチドを含む医薬組成物、ならびに、当該ポリペプチドを含む抗原が除去又は低減若しくはポリペプチドを切断又は取り除かれた食品原料または食用加工品に関する。本発明はさらに、対象物における抗原の有無を判定するためのテスターに関する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)