Search International and National Patent Collections

1. (WO2018158728) CARBON DIOXIDE BASED CHROMATOGRAPHY SYSTEMS INCLUDING MULTIPLE PRESSURE CONTROL DEVICES

Pub. No.:    WO/2018/158728    International Application No.:    PCT/IB2018/051322
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Fri Mar 02 00:59:59 CET 2018
IPC: G01N 30/32
B01D 15/40
Applicants: WATERS TECHNOLOGIES CORPORATION
Inventors: FOGWILL, Michael O.
SHREVE, Joshua A.
Title: CARBON DIOXIDE BASED CHROMATOGRAPHY SYSTEMS INCLUDING MULTIPLE PRESSURE CONTROL DEVICES
Abstract:
The present disclosure relates to methodologies, systems and devices for controlling pressure of a mobile phase in a CO2-based chromatography system. A pump is used to pump a mobile phase containing CO2 and is located upstream of a chromatography column. A primary pressure control element is located downstream of the chromatography column and controls the pressure of the mobile phase within the column. A secondary pressure control element is located downstream of the primary pressure control element and maintains the pressure of the mobile phase above a threshold value between an outlet of the primary pressure control element and the point of detection within a detector. The detector is located downstream of both the primary pressure control element and the secondary pressure control element.