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1. (WO2018158457) POPULATION-BASED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
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Pub. No.: WO/2018/158457 International Application No.: PCT/EP2018/055232
Publication Date: 07.09.2018 International Filing Date: 02.03.2018
IPC:
G01N 33/50 (2006.01) ,G01N 33/569 (2006.01) ,A61K 39/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
TREOS BIO ZRT [HU/HU]; Viola utca 2 8200 Veszprem, HU
Inventors:
LISZIEWICZ, Julianna; HU
MOLNÁR, Levente; HU
TŐKE, Enikő, R.; HU
TOTH, József; HU
LORINCZ, Orsolya; HU
CSISZOVSZKI, Zsolt; HU
SOMOGYI, Eszter; HU
PÁNTYA, Katalin; HU
MEGYESI, Mónika; HU
Agent:
KIMBLIN, Nicola; GB
Priority Data:
1703809.209.03.2017GB
17159242.103.03.2017EP
17159243.903.03.2017EP
Title (EN) POPULATION-BASED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
(FR) PLATE-FORME D'IDENTIFICATION DE PEPTIDE IMMUNOGÈNE REPOSANT SUR UNE POPULATION
Abstract:
(EN) The disclosurerelates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing pharmaceutical compositions comprising such polypeptide fragments, pharmaceutical compositions comprising such polypeptide fragments, and methods of treatment using such compositions. The methods comprise identifying a fragment of the polypeptide that binds to multiple HLA of individual subjects.
(FR) L'invention concerne des méthodes d'identification de fragments d'un polypeptide qui sont immunogènes pour un sujet humain spécifique, des méthodes de préparation de compositions pharmaceutiques comprenant de tels fragments polypeptidiques, des compositions pharmaceutiques comprenant de tels fragments polypeptidiques, et des méthodes de traitement utilisant de telles compositions. Les méthodes consistent à identifier un fragment du polypeptide qui se lie à de multiples HLA de sujets individuels.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)