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1. (WO2018158456) PERSONALISED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
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Pub. No.: WO/2018/158456 International Application No.: PCT/EP2018/055231
Publication Date: 07.09.2018 International Filing Date: 02.03.2018
IPC:
A61K 39/00 (2006.01) ,G01N 33/50 (2006.01) ,G01N 33/569 (2006.01) ,A61K 39/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
Applicants:
TREOS BIO ZRT [HU/HU]; Viola utca 2 8200 Veszprem, HU
Inventors:
LISZIEWICZ, Julianna; HU
MOLNÁR, Levente; HU
TŐKE, Enikő, R.; HU
TOTH, József; HU
LORINCZ, Orsolya; HU
CSISZOVSZKI, Zsolt; HU
SOMOGYI, Eszter; HU
PÁNTYA, Katalin; HU
MEGYESI, Mónika; HU
Agent:
KIMBLIN, Nicola; GB
Priority Data:
1703809.209.03.2017GB
17159242.103.03.2017EP
17159243.903.03.2017EP
Title (EN) PERSONALISED IMMUNOGENIC PEPTIDE IDENTIFICATION PLATFORM
(FR) PLATEFORME PERSONNALISÉE D'IDENTIFICATION DE PEPTIDE IMMUNOGÈNE
Abstract:
(EN) The disclosure relates to methods of identifying fragments of a polypeptide that are immunogenic for a specific human subject, methods of preparing personalised pharmaceutical compositions comprising such polypeptide fragments, human subject-specific pharmaceutical compositions comprising such polypeptide fragments, and methods of treatment using such compositions. The methods comprise identifying a fragment of the polypeptide that binds to multiple HLA of the subject.
(FR) La présente invention concerne des procédés d'identification de fragments d'un polypeptide qui sont immunogènes pour un sujet humain spécifique, des procédés de préparation de compositions pharmaceutiques personnalisées comprenant de tels fragments polypeptidiques, des compositions pharmaceutiques spécifiques d'un sujet humain comprenant de tels fragments polypeptidiques, et des méthodes de traitement utilisant de telles compositions. Les procédés consistent à identifier un fragment du polypeptide qui se lie à de multiples HLA du sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)