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1. (WO2018158455) PEPTIDE VACCINES
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Pub. No.: WO/2018/158455 International Application No.: PCT/EP2018/055230
Publication Date: 07.09.2018 International Filing Date: 02.03.2018
IPC:
G01N 33/569 (2006.01) ,A61K 38/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
TREOS BIO ZRT. [HU/HU]; Viola utca 2 8200 Veszprem, HU
Inventors:
LISZIEWICZ, Julianna; HU
MOLNÁR, Levente; HU
TŐKE, Enikő; HU
TOTH, József; HU
LORINCZ, Orsolya; HU
CSISZOVSZKI, Zsolt; HU
SOMOGYI, Eszter; HU
PÁNTYA, Katalin; HU
MEGYESI, Mónika; HU
Agent:
KIMBLIN, Nicola; GB
Priority Data:
1703809.209.03.2017GB
17159242.103.03.2017EP
17159243.903.03.2017EP
Title (EN) PEPTIDE VACCINES
(FR) VACCINS PEPTIDIQUES
Abstract:
(EN) The disclosure relates to polypeptides and pharmaceutical compositions comprising polypeptides that find use in the prevention or treatment of cancer, in particular breast cancer, ovarian cancer and colorectal cancer. The disclosure also relates to methods of inducing a cytotoxic T cell response in a subject or treating cancer by administering pharmaceutical compositions comprising the peptides, and companion diagnostic methods of identifying subjects for treatment. The peptides comprise T cell epitopes that are immunogenic in a high percentage of patients.
(FR) L'invention concerne des polypeptides et des compositions pharmaceutiques comprenant les polypeptides qui sont utiles dans la prévention ou le traitement du cancer, en particulier du cancer du sein, du cancer de l'ovaire et du cancer colorectal. L'invention concerne également des procédés d'induction d'une réponse des lymphocytes T cytotoxiques chez un sujet ou de traitement du cancer par l'administration de compositions pharmaceutiques comprenant les peptides, et des procédés de diagnostic compagnon pour identifier des sujets pour un traitement. Les peptides comprennent des épitopes de lymphocytes T qui sont immunogènes dans un pourcentage élevé de patients.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)