Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018158350) COMBINATION OF AN ANTI-CD16A ANTIBODY WITH A CYTOKINE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/158350 International Application No.: PCT/EP2018/054990
Publication Date: 07.09.2018 International Filing Date: 28.02.2018
IPC:
A61K 39/395 (2006.01) ,C07K 16/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
AFFIMED GMBH [DE/DE]; Im Neuenheimer Feld 582 69120 Heidelberg, DE
Inventors:
KOCH, Joachim; DE
TREDER, Martin; DE
PAHL, Jens; DE
REUSCH, Uwe; DE
ROSS, Thorsten; DE
RAJKOVIC, Erich; DE
CERWENKA, Adelheid; DE
Agent:
HUBER & SCHÜSSLER; Truderinger Strasse 246 81825 Munich, DE
Priority Data:
17158563.128.02.2017EP
Title (EN) COMBINATION OF AN ANTI-CD16A ANTIBODY WITH A CYTOKINE
(FR) COMBINAISON D'UN ANTICORPS ANTI-CD16A AVEC UNE CYTOKINE
Abstract:
(EN) The invention relates to an anti-CD16A antigen binding protein for use in NK cell based immunotherapy, wherein the anti-CD16A antigen binding protein is to be administered intermittently and in combination with a cytokine. In certain embodiments the antigen binding protein is a tetravalent and bispecific CD30/CD16A tandem diabody.
(FR) L'invention concerne une protéine de liaison à l'antigène anti-CD16A destinée à être utilisée dans une immunothérapie à base de cellules NK (cellules tueuses naturelles), la protéine de liaison à l'antigène anti-CD16A étant destinée à être administrée par intermittence et en combinaison avec une cytokine. Dans certains modes de réalisation, la protéine de liaison à l'antigène est un diabody en tandem CD30/CD16A tétravalent et bispécifique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)