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1. (WO2018158319) FERMENTATION REACTOR AND FERMENTATION PROCESS

Pub. No.:    WO/2018/158319    International Application No.:    PCT/EP2018/054944
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Thu Mar 01 00:59:59 CET 2018
IPC: C12M 1/00
B01D 19/00
C12M 1/34
C12M 1/36
Applicants: UNIBIO A/S
Inventors: HIDAYAT, Budi, Juliman
CHRISTENSEN, Ib
PEDERSEN, Patrick, Nicklas
NANDY, Subir, Kumar
BUSCH-LARSEN, Henrik
Title: FERMENTATION REACTOR AND FERMENTATION PROCESS
Abstract:
The present invention relates to a fermentation reactor comprising a loop-part having a circulation pump, a degassing-tank, and a fermentation liquid outlet for withdrawing fermentation liquid from the fermentation reactor, said degassing-tank comprises: (i) a first outlet connecting the degassing-tank to a first leg of the loop-part and allowing fermentation liquid present in the degassing-tank to flow into the loop-part; (ii) a first inlet connecting the degassing-tank to a second leg of the loop-part, allowing fermentation liquid present in the loop-part to flow into the degassing-tank; and (iii) a vent tube for discharging effluent gasses from the degassing tank, such as CO2; wherein one or more of the following criteria applies; (a) (a) wherein the first outlet and/or the first leg of the loop-part is provided with an anti-vortex device to avoid flooding of the circulation pump; (b) wherein a ratio between a volume (internal volume determined as m3) of the degassing-tank relative to a volume (internal volume determined as m3) of the loop-part is in the range of 0.25: 1 to 20: 1; (c) wherein a numerical ratio between a volume (internal volume, determined as m3) of the degassing-tank relative to a cross section area of the first leg and/or the cross section area (determined as m2) of second leg is in the range of 10: 1 to 250: 1; (d) wherein a cross section area of the first leg (determined as m2) is 10% or more larger than a cross section area of the second leg (determined as m2), (e) wherein a cross section area of the second leg (determined as m2) is 10% or more larger than a cross section area of the first leg (determined as m2), or (f) any combination of criteria (a) to (e).