Search International and National Patent Collections
|1. (WO2018157851) PERIOSTEAL REPAIR SHEET FOR GUIDED BONE REGENERATION, PREPARATION METHOD AND USE|
|Applicants:||BEIJING BIOSIS HEALING BIOLOGICAL TECHNOLOGY CO., LTD
|Title:||PERIOSTEAL REPAIR SHEET FOR GUIDED BONE REGENERATION, PREPARATION METHOD AND USE|
Disclosed are a periosteal repair sheet for guided bone regeneration, a preparation method and the use. The periosteal repair sheet comprises a high-porosity loose active layer and a low-porosity dense basal layer, collagen, polysaccharide substances and active factors; the loose active layer further comprises active factors for guided bone regeneration; and the periosteal repair sheet, when implanted into the body, can be degraded and absorbed. The preparation method and use thereof are also addressed. The repair sheet, forming a dual-layer composite structure with a loose upper layer and a dense lower layer, is conducive to growth-in of cells, and is capable of improving the repair speed of tissues; the dense layer is an immunogen-removed substrate, and the substrate layer has an isolating effect, effectively protecting the repaired tissues; and a morphogenetic bone protein is added for the repair of periosteal injuries and defects.