Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018157742) CRYSTALLINE FORM OF SALT OF SB-939, PREPARATION METHOD THEREFOR, AND USE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/157742 International Application No.: PCT/CN2018/076609
Publication Date: 07.09.2018 International Filing Date: 13.02.2018
IPC:
C07D 235/08 (2006.01) ,A61K 31/4184 (2006.01) ,A61K 31/165 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/02 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
235
Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02
condensed with carbocyclic rings or ring systems
04
Benzimidazoles; Hydrogenated benzimidazoles
06
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
08
Radicals containing only hydrogen and carbon atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4184
condensed with carbocyclic rings, e.g. benzimidazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
02
specific for leukemia
Applicants:
苏州科睿思制药有限公司 CRYSTAL PHARMACEUTICAL (SUZHOU) CO., LTD. [CN/CN]; 中国江苏省 苏州市工业园区星湖街218号生物纳米园B4-301赵林林 ZHAO, Linlin B4-301, Biobay, 218 Xinghu Street, Suzhou Industrial Park Suzhou, Jiangsu 215123, CN
Inventors:
陈敏华 CHEN, Minhua; CN
张炎锋 ZHANG, Yanfeng; CN
高慧 GAO, Hui; CN
刘启月 LIU, Qiyue; CN
张晓宇 ZHANG, Xiaoyu; CN
Priority Data:
201710112053.628.02.2017CN
Title (EN) CRYSTALLINE FORM OF SALT OF SB-939, PREPARATION METHOD THEREFOR, AND USE
(FR) FORME CRISTALLINE DE SEL DE SB-939, PROCÉDÉ DE PRÉPARATION ET UTILISATION ASSOCIÉE
(ZH) SB-939的盐的晶型及其制备方法和用途
Abstract:
(EN) The present invention relates to a crystalline form of a salt of compound (I), a preparation method therefor, and a use. The new crystalline form CS2 has low hygroscopicity, good stability, high crystalline form purity and high solubility. The present invention provides a new and better alternative for the preparation of a drug containing compound (I), and has considerable significance for drug development.
(FR) La présente invention concerne une forme cristalline d'un sel du composé (I), un procédé de préparation et une utilisation associés. La nouvelle forme cristalline CS2 a une faible hygroscopicité, une bonne stabilité, une pureté de forme cristalline élevée et une solubilité élevée. La présente invention concerne une alternative nouvelle et meilleure pour la préparation d'un composé contenant un médicament (I), et a une importance considérable pour le développement de médicaments.
(ZH) 本发明涉及化合物(I)的盐的晶型及其制备方法和用途。本发明提供的新晶型CS2的引湿性较低、稳定性良好、晶型纯度高且溶解度高。为含化合物(I)药物的制备提供了新的更好的选择,对于药物开发具有非常重要的意义。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)