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1. (WO2018157696) ATP1A1-TARGETING POLYPEPTIDE AND USE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/157696 International Application No.: PCT/CN2018/075056
Publication Date: 07.09.2018 International Filing Date: 02.02.2018
IPC:
C07K 7/06 (2006.01) ,C07K 7/56 (2006.01) ,A61K 47/64 (2017.01) ,A61K 51/08 (2006.01) ,A61K 49/00 (2006.01) ,A61P 35/00 (2006.01) ,A61K 101/02 (2006.01) ,A61K 101/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
50
Cyclic peptides containing at least one abnormal peptide link
54
with at least one abnormal peptide link in the ring
56
the cyclisation not occurring through 2,4-diamino-butanoic acid
[IPC code unknown for A61K 47/64]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
101
Radioactive non-metals
02
Halogens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
101
Radioactive non-metals
Applicants:
中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER [CN/CN]; 中国广东省广州市 越秀区东风东路651号 No. 651, Dongfeng East Road, Yuexiu Guangzhou, Guangdong 510060, CN
Inventors:
曾木圣 ZENG, Musheng; CN
冯国开 FENG, Guokai; CN
王茜 WANG, Qian; CN
叶晓璇 YE, Xiaoxuan; CN
肖炜 XIAO, Wei; CN
李满枝 LI, Manzhi; CN
Agent:
广州嘉权专利商标事务所有限公司 JIAQUAN IP LAW FIRM; 中国广东省广州市 天河区黄埔大道西100号富力盈泰广场A栋910张萍 ZHANG, Ping No. 910, Building A, Winner Plaza, No. 100, West Huangpu Avenue, Tianhe District Guangzhou, Guangdong 510627, CN
Priority Data:
201710117296.901.03.2017CN
Title (EN) ATP1A1-TARGETING POLYPEPTIDE AND USE
(FR) POLYPEPTIDE CIBLANT ATP1A1 ET UTILISATION
(ZH) ATP1A1靶向多肽及应用
Abstract:
(EN) Disclosed are an ATP1A1-targeting polypeptide and the use thereof. The motif of the ATP1A1-targeting polypeptide is SISSLTH, and 1-3 amino acids are optionally linked to the C-terminus and/or N-terminus of the motif. The ATP1A1-targeting polypeptide can target ATP1A1, and has an important application value in the molecular diagnosis and targeted therapy of tumours.
(FR) L'invention concerne un polypeptide ciblant ATP1A1 et son utilisation. Le motif du polypeptide de ciblage ATP1A1 est le SISSLTH, et les acides aminés 1-3 sont éventuellement liés à l'extrémité C-terminale et/ou à l'extrémité N-terminale du motif. Le polypeptide de ciblage ATP1A1 de l'invention peut cibler ATP1A1, et présente une valeur d'application importante dans le diagnostic moléculaire et la thérapie ciblée de tumeurs.
(ZH) 本发明公开了一种ATP1A1靶向多肽及其应用。ATP1A1靶向多肽的基序为SISSLTH,基序的C端和/或N端可选连接有1-3个氨基酸。该ATP1A1靶向多肽可以靶向ATP1A1,在肿瘤的分子诊断和靶向治疗中具有重要应用价值。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)