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1. (WO2018146698) IMPROVED METHOD FOR THE PREPARATION OF SULFOBUTYLETHER BETA CYCLODEXTRIN SODIUM
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Pub. No.: WO/2018/146698 International Application No.: PCT/IN2018/050063
Publication Date: 16.08.2018 International Filing Date: 07.02.2018
IPC:
A61K 31/724 (2006.01) ,C08B 37/16 (2006.01) ,A61P 43/00 (2006.01) ,A61K 9/00 (2006.01) ,C08L 5/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716
Glucans
724
Cyclodextrins
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
B
POLYSACCHARIDES; DERIVATIVES THEREOF
37
Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
16
Cyclodextrin; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
5
Compositions of polysaccharides or of their derivatives not provided for in group C08L1/ or C08L3/142
16
Cyclodextrin; Derivatives thereof
Applicants:
BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. [IN/IN]; Plot Number 92, 1-98/2/92, Phase II, Kavuri Hills, Jubilee Hills Hyderabad 500033, IN
Inventors:
PULLAGURLA, Manik Reddy; IN
PITTA, Bhaskar Reddy; IN
NAMANA, Suresh Babu; IN
NAGARAPU, Radha; IN
RANGISETTY, Jagadeesh Babu; IN
Agent:
HASAN, Afzal; IN
HASAN, Vatsala Singh; IN
Priority Data:
20174100449307.02.2017IN
Title (EN) IMPROVED METHOD FOR THE PREPARATION OF SULFOBUTYLETHER BETA CYCLODEXTRIN SODIUM
(FR) PROCÉDÉ AMÉLIORÉ DE PRÉPARATION DE SULFOBUTYLÉTHER BÊTA-CYCLODEXTRINE SODIQUE
Abstract:
(EN) The present invention relates to an improved method for the synthesis of sulfobutylether beta cyclodextrin sodium and to provide an amorphous form of sulfobutylether beta cyclodextrin sodium having a 1,4-butane sultone content less than 0.5 ppm. The present invention further provides sulfobutylether beta cyclodextrin sodium containing less than 35 IU/g of Bacterial endotoxins.
(FR) L'invention concerne un procédé amélioré de synthèse de sulfobutyléther bêta-cyclodextrine sodique. L'invention concerne également une forme amorphe de sulfobutyléther bêta-cyclodextrine sodique ayant une teneur en 1,4-butane-sultone inférieure à 0,5 ppm. L'invention concerne également du sulfobutyléther bêta-cyclodextrine sodique contenant moins de 35 UI/g d'endotoxines bactériennes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)