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1. (WO2018146545) HIGHLY PURIFIED EICOSAPENTAENOIC ACID, AS FREE FATTY ACID, REDUCES FECAL CALPROTECTIN LEVELS AND PREVENTS CLINICAL RELAPSE IN ULCERATIVE COLITIS PATIENTS

Pub. No.:    WO/2018/146545    International Application No.:    PCT/IB2018/000168
Publication Date: Fri Aug 17 01:59:59 CEST 2018 International Filing Date: Wed Feb 07 00:59:59 CET 2018
IPC: A61K 31/557
A61P 1/00
A61K 45/06
Applicants: S.L.A. PHARMA AG
Inventors: BELLUZZI, Andrea
Title: HIGHLY PURIFIED EICOSAPENTAENOIC ACID, AS FREE FATTY ACID, REDUCES FECAL CALPROTECTIN LEVELS AND PREVENTS CLINICAL RELAPSE IN ULCERATIVE COLITIS PATIENTS
Abstract:
The present invention relates to a method of administering an effective dose of highly purified eicosapentaenoic acid as free-fatty acid (EPA-FFA) to reduce fecal calprotectin levels and reduce the risk of clinical relapse in UC patients. The eicosapentaenoic acid, in the free fatty acid (EPA-FFA) form, has a purity of at least 95%, and more preferably at least 99%.