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1. (WO2018146275) A COMPANION DIAGNOSTIC METHOD FOR USE IN THE TREATMENT OF CYSTIC FIBROSIS WITH ALGINATE OLIGOMERS
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Pub. No.: WO/2018/146275 International Application No.: PCT/EP2018/053347
Publication Date: 16.08.2018 International Filing Date: 09.02.2018
IPC:
G01N 21/359 (2014.01) ,A61K 31/00 (2006.01) ,G01N 21/35 (2014.01) ,G01N 21/552 (2014.01)
[IPC code unknown for G01N 21/359]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
25
Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
31
Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
35
using infra-red light
[IPC code unknown for G01N 21/552]
Applicants:
ALGIPHARMA AS [NO/NO]; Industriveien 33 N-1337 Sandvika N-1337 Sandvika, NO
Inventors:
LEWIS, Paul; GB
DESSEN, Arne; NO
RYE, Philip; NO
Agent:
DEHNS; St Bride's House 10 Salisbury Square London Greater London EC4Y 8JD, GB
Priority Data:
1702161.909.02.2017GB
Title (EN) A COMPANION DIAGNOSTIC METHOD FOR USE IN THE TREATMENT OF CYSTIC FIBROSIS WITH ALGINATE OLIGOMERS
(FR) PROCÉDÉ DE DIAGNOSTIC COMPAGNON DESTINÉ À ÊTRE UTILISÉ DANS LE TRAITEMENT DE LA MUCOVISCIDOSE AVEC DES OLIGOMÈRES D'ALGINATE
Abstract:
(EN) The present invention provides a diagnostic method which may be used to determine the likelihood that a patient with cystic fibrosis will respond to treatment with an alginate oligomer. The method is based on analysingthe IR absorbance values and/or transmittance values, in particular a Fourier transform infrared spectroscopy (FTIR) spectrum, of a mucus sample from the respiratory system of a CF patient at certain specific wavenumbers.
(FR) La présente invention concerne un procédé de diagnostic qui peut être utilisé pour déterminer la probabilité qu'un patient atteint de mucoviscidose réponde au traitement avec un oligomère d'alginate. Le procédé est basé sur l'analyse des valeurs d'absorbance IR et/ou des valeurs de transmittance, en particulier d'un spectre de spectroscopie infrarouge à transformée de Fourier (FTIR), d'un échantillon de mucus provenant du système respiratoire d'un patient atteint de mucoviscidose à certains nombres d'ondes spécifiques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)