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1. (WO2018145588) USE OF CELL VESICLE FORMULATION COMBINED WITH LOW DOSE RADIOTHERAPY IN PREPARATION OF ANTITUMOR DRUGS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/145588 International Application No.: PCT/CN2018/074522
Publication Date: 16.08.2018 International Filing Date: 30.01.2018
IPC:
A61K 45/00 (2006.01) ,A61K 47/46 (2006.01) ,A61N 5/00 (2006.01) ,A61K 35/12 (2015.01) ,A61K 35/13 (2015.01) ,A61K 31/519 (2006.01) ,A61K 31/704 (2006.01) ,A61K 33/24 (2006.01) ,A61K 9/14 (2006.01) ,A61K 9/50 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
46
Ingredients of undetermined constitution or reaction products thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
5
Radiation therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
[IPC code unknown for A61K 35/13]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
湖北盛齐安生物科技股份有限公司 HUBEI SOUNDNY BIO TECH CO., LTD. [CN/CN]; 中国湖北省武汉市 东湖新技术开发区高新大道666号C4栋4楼 4/F, Building C4, No. 666 Gaoxin Avenue East Lake Hi-Tech Development Zone Wuhan, Hubei 430000, CN
Inventors:
黄波 HUANG, Bo; CN
Agent:
北京律诚同业知识产权代理有限公司 LECOME INTELLECTUAL PROPERTY AGENT LTD.; 中国北京市 海淀区知春路甲48号盈都大厦B16层 Fl. 16, Tower B, Indo Mansion No. 48-Jia Zhichun Road, Haidian District Beijing 100098, CN
Priority Data:
201710071569.009.02.2017CN
Title (EN) USE OF CELL VESICLE FORMULATION COMBINED WITH LOW DOSE RADIOTHERAPY IN PREPARATION OF ANTITUMOR DRUGS
(FR) UTILISATION D'UNE PRÉPARATION DE VÉSICULE CELLULAIRE, UTILISÉE EN ASSOCIATION AVEC UNE RADIOTHÉRAPIE À FAIBLE DOSE, DANS LA PRÉPARATION DE MÉDICAMENTS ANTI-TUMORAUX
(ZH) 细胞囊泡制剂与低剂量放疗联合在制备抗肿瘤药物中的应用
Abstract:
(EN) Provided is a use of cell vesicle formulation combined with low dose radiotherapy in the preparation of antitumor drugs. The cell vesicle formulation is derived from apoptotic tumor cells and wraps a chemotherapeutic agent, and the low dose radiotherapy is a radiation therapy with a lower total dose of radiation to treat the tumor. Optionally, the chemotherapeutic agent is selected from the group consisting of cisplatin, methotrexate and doxorubicin.
(FR) L'invention concerne l'utilisation d'une préparation de vésicule cellulaire, en association avec une radiothérapie à faible dose, dans la préparation de médicaments anti-tumoraux. La préparation de vésicule cellulaire est dérivée de cellules tumorales apoptotiques et enveloppe un agent chimiothérapeutique, et la radiothérapie à faible dose est une radiothérapie ayant une plus faible dose totale de rayonnement pour traiter la tumeur. Facultativement, l'agent chimiothérapeutique est sélectionné dans le groupe constitué par le cisplatine, le méthotrexate et la doxorubicine.
(ZH) 细胞囊泡制剂与低剂量放疗联合在制备治疗肿瘤药物中的应用,所述细胞囊泡制剂源自凋亡的肿瘤细胞并包裹了化疗药物,所述低剂量放疗为以治疗所述肿瘤的放射线总剂量较低的放射治疗,可选地,所述化疗药物选自顺铂、甲氨蝶呤和阿霉素。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)