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1. (WO2018145553) CO-CRYSTALS OF SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF

Pub. No.:    WO/2018/145553    International Application No.:    PCT/CN2018/072186
Publication Date: Fri Aug 17 01:59:59 CEST 2018 International Filing Date: Fri Jan 12 00:59:59 CET 2018
IPC: A61K 31/198
A61K 47/12
C07C 229/12
C07C 57/15
C07C 59/255
C07D 307/62
A61P 25/00
Applicants: SYNEURX INTERNATIONAL (TAIWAN) CORP.
Inventors: TSAI, Guochuan Emil
WANG, Ching-Cheng
HSIEH, Tien-Lan
Title: CO-CRYSTALS OF SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF
Abstract:
The present disclosure provides co-crystals of a substituted glycine compound and a co-former compound of Formula (I), compositions comprising such, and uses thereof in treating and/or reducing the risk for a neuropsychiatricdisorder (e.g., schizophrenia, psychotic disorders, depressive disorders, suicidal ideation and/or behavior, obsessive compulsive disorderor Alzheimer's disease). Also provided herein are methods for preparing the co-crystals.