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1. (WO2018145213) CANNABINOID-CONTAINING FATTY ACID FORMULATIONS FOR TREATING DISORDERS OF THE NERVOUS SYSTEM
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Pub. No.: WO/2018/145213 International Application No.: PCT/CA2018/050153
Publication Date: 16.08.2018 International Filing Date: 09.02.2018
IPC:
A61K 31/352 (2006.01) ,A61K 31/05 (2006.01) ,A61K 31/202 (2006.01) ,A61K 36/185 (2006.01) ,A61P 25/00 (2006.01) ,C07C 39/23 (2006.01) ,C07C 57/03 (2006.01) ,C07D 311/80 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05
Phenols
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202
having three or more double bonds, e.g. linolenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
39
Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
23
polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
57
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
02
with only carbon-to-carbon double bonds as unsaturation
03
Monocarboxylic acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
78
Ring systems having three or more relevant rings
80
Dibenzopyrans; Hydrogenated dibenzopyrans
Applicants:
BODHI RESEARCH & DEVELOPMENT INC. [CA/CA]; 59 East Liberty Street East, Suite 2503 Toronto, Ontario M6K 3R1, CA
Inventors:
JHA, Neilank K.; CA
Agent:
KINGWELL, Brian; CA
FERANCE, Stephen; CA
THORNE, Lisa; CA
WILKE, Mark; CA
SALISBURY, Clare; CA
SECHLEY, Konrad; CA
RIPLEY, Roch; CA
LEE, Brian; CA
ZIESCHE, Sonia; CA
Priority Data:
62/457,05909.02.2017US
Title (EN) CANNABINOID-CONTAINING FATTY ACID FORMULATIONS FOR TREATING DISORDERS OF THE NERVOUS SYSTEM
(FR) FORMULES D'ACIDES GRAS CONTENANT DES CANNABINOÏDES POUR TRAITER DES TROUBLES DU SYSTÈME NERVEUX
Abstract:
(EN) Pharmaceutical compositions comprising cannabidiol (CBD), tetrahydrocannabinol (THC), and select omega-3 fatty acids are provided. The CBD and THC are present in a weight ratio of CBD:THC of 10:1 to 20:1. The omega-3 fatty acids comprise eicosapentaenoic acid and/or docosahexaenoic acid. Such compositions are useful in the treatment and prevention of traumatic brain injuries, concussions, post-concussive brain injury (PCS), and complications arising from such injuries.
(FR) La présente invention concerne des compositions pharmaceutiques comprenant du cannabidiol (CBD), du tétrahydrocannabinol (THC) et des acides gras oméga-3 choisis. Le CBD et le THC sont présents dans un rapport massique CBD : THC de 10 : 1 à 20 : 1. Les acides gras oméga-3 comprennent de l'acide eicosapenténoïque et/ou de l'acide docosahexénoïque. De telles compositions sont utiles dans le traitement prophylactique et thérapeutique de lésions cérébrales traumatiques, de commotions, de lésions cérébrales post-commotion (PCS) et des complications dues à de telles lésions.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)