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1. (WO2018144996) METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/144996 International Application No.: PCT/US2018/016848
Publication Date: 09.08.2018 International Filing Date: 05.02.2018
IPC:
C12N 1/00 (2006.01) ,C12N 1/20 (2006.01) ,C12N 1/21 (2006.01) ,C12N 9/00 (2006.01) ,C12N 15/00 (2006.01) ,C12N 15/52 (2006.01) ,C12P 5/00 (2006.01)
Applicants: MANUS BIO, INC.[US/US]; 1030 Massachusetts Avenue Cambridge, MA 02138, US
Inventors: KUMARAN, Ajikumar, Parayil; US
LIM, Chin-giaw; US
GHOSH, Souvik; US
PIRIE, Christopher; US
DONALD, Jason; US
LOVE, Aaron; US
NAN, Hong; US
TSENG, Hsien-chung; US
SANTOS, Christine Nicole, S.; US
PHILIPPE, Ryan; US
Agent: HAYMAN, Mark, L.; US
ALTIERI, Stephen; US
LIN, Yi-chia; US
FRANK, Steven, J.; US
CURRIE, Matthew, T.; US
Priority Data:
62/454,12103.02.2017US
Title (EN) METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
(FR) INGÉNIERIE MÉTABOLIQUE POUR LA PRODUCTION MICROBIENNE DE PRODUITS TERPÉNOÏDES
Abstract: front page image
(EN) In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
(FR) Dans divers aspects et modes de réalisation, l'invention concerne des souches bactériennes et des procédés de fabrication de produits terpéniques et terpénoïdes. L'invention concerne des souches bactériennes à flux de carbone amélioré dans la voie MEP, pour augmenter ainsi le rendement en terpène et/ou en produit terpénoïde par fermentation avec des sources de carbone telles que le glucose.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)