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1. (WO2018144858) METHODS OF IMPROVING BONE-SOFT TISSUE HEALING USING ELECTROSPUN FIBERS
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Pub. No.: WO/2018/144858 International Application No.: PCT/US2018/016638
Publication Date: 09.08.2018 International Filing Date: 02.02.2018
IPC:
A61F 2/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
08
Muscles; Tendons; Ligaments
Applicants:
NANOFIBER SOLUTIONS, INC. [US/US]; 4389 Weaver Court North Hilliard, Ohio 43026, US
Inventors:
JOHNSON, Jed; US
CHAKROFF, Jason; US
OHST, Devan; US
COHEN, Brian; US
ROMEO, Anthony; US
Agent:
BOWERS, Megan E.; US
Priority Data:
62/453,73702.02.2017US
62/583,53009.11.2017US
62/596,17908.12.2017US
Title (EN) METHODS OF IMPROVING BONE-SOFT TISSUE HEALING USING ELECTROSPUN FIBERS
(FR) PROCÉDÉS D’AMÉLIORATION DE LA GUÉRISON DE TISSU OSSEUX-MOU EN UTILISANT DES FIBRES ÉLECTROFILÉES
Abstract:
(EN) The instant disclosure is directed to methods of improving bone-soft tissue healing using biocompatible electrospun polymer fibers. In one embodiment, a method may include locating a portion of a subject's bone, affixing a tendon or ligament to the bone using a hardware fixture, and placing a patch comprising at least one electrospun polymer fiber in physical communication with both the bone and the tendon or ligament. In some embodiments, the bone may be a humerus, and the tendon or ligament may be a supraspinatus tendon. In certain embodiments, the patch may comprise substantially parallel electrospun polymer fibers, and may be placed such that the fibers are also substantially parallel with the long axis of the tendon or ligament.
(FR) La présente invention concerne des procédés d’amélioration de la guérison de tissu osseux-mou en utilisant des fibres polymères électrofilées biocompatibles. Selon un mode de réalisation, un procédé peut comprendre la localisation d’une partie de l'os d'un patient, l’apposition d’un tendon ou d’un ligament à l’os en utilisant un appareillage, et la pose d’un patch comprenant au moins une fibre polymère électrofilée en communication physique tant avec l’os qu'avec le tendon ou le ligament. Selon certains modes de réalisation, l’os peut être un humérus, et le tendon ou le ligament peuvent être un tendon sus-épineux. Selon certains modes de réalisation, le patch peut comprendre des fibres polymères électrofilées sensiblement parallèles, et peut être posé de sorte que les fibres soient également sensiblement parallèles à l’axe long du tendon ou du ligament.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)