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1. (WO2018144816) METABOLIC BIOMARKERS FOR COGNITIVE ABILITY

Pub. No.:    WO/2018/144816    International Application No.:    PCT/US2018/016590
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Sat Feb 03 00:59:59 CET 2018
IPC: G01N 33/48
G01N 33/50
A61P 25/28
Applicants: GEORGETOWN UNIVERSITY
UNIVERSITY OF ROCHESTER
Inventors: MAPSTONE, Mark E.
FEDEROFF, Howard J.
FIANDACA, Massimo S.
CHEEMA, Amrita K.
Title: METABOLIC BIOMARKERS FOR COGNITIVE ABILITY
Abstract:
The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's metabolite profile and comparing the value of the subject's metabolite profile with the value of a normal metabolite profile. A change in the value of the subject's metabolite profile, over normal values is indicative that the subject has a decreased risk of suffering from future memory impairment compared to a normal individual.