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1. (WO2018144800) COMPOSITIONS AND METHODS FOR KELOIDLESS HEALING

Pub. No.:    WO/2018/144800    International Application No.:    PCT/US2018/016564
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Sat Feb 03 00:59:59 CET 2018
IPC: C07C 253/30
C07C 259/18
C07C 303/40
Applicants: HEALTH RESEARCH, INC.
AOKI, Masayo
Inventors: AOKI, Masayo
TAKABE, Kazuaki
Title: COMPOSITIONS AND METHODS FOR KELOIDLESS HEALING
Abstract:
Provided are compositions, methods and devices for reducing scarring during healing of a tissue wound. The compositions and methods involve use of sphingosine-1 -phosphate (SIP), and/or an expression vector that encodes sphingosine kinasel (SphKl). The compositions can be combined with other agents and implements, such as biocompatible nanoparticles, and medical devices involved with promoting wound healing. The approaches can reduce formation or prevent the occurrence of keloids.