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1. (WO2018144765) HIGH RESOLUTION MULTI-FUNCTION AND CONFORMAL ELECTRONICS DEVICE FOR DIAGNOSIS AND TREATMENT OF CARDIAC ARRHYTHMIAS
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Pub. No.: WO/2018/144765 International Application No.: PCT/US2018/016499
Publication Date: 09.08.2018 International Filing Date: 01.02.2018
IPC:
A61B 5/00 (2006.01) ,A61B 5/03 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/11 (2006.01) ,A61B 5/0205 (2006.01) ,A61B 5/042 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
03
Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
103
Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
11
Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
0205
Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
0402
Electrocardiography, i.e. ECG
0408
Electrodes specially adapted therefor
042
for introducing into the body
Applicants:
THE GEORGE WASHINGTON UNIVERSITY [US/US]; Rice Hall, Suite 601 2121 I Street, NW Washington, District of Columbia 20052, US
Inventors:
EFIMOV, Igor R.; US
ARAS, Kedar; US
ROGERS, John A.; US
GREMI, Erdit; US
POSPISIL, David; CZ
Agent:
WEISSMAN, Peter S.; US
GREENBAUM, Michael C.; US
Priority Data:
62/453,18401.02.2017US
62/528,75805.07.2017US
Title (EN) HIGH RESOLUTION MULTI-FUNCTION AND CONFORMAL ELECTRONICS DEVICE FOR DIAGNOSIS AND TREATMENT OF CARDIAC ARRHYTHMIAS
(FR) DISPOSITIF ÉLECTRONIQUE MULTIFONCTION, CONFORMÉ ET À HAUTE RÉSOLUTION POUR LE DIAGNOSTIC ET LE TRAITEMENT DES ARYTHMIES CARDIAQUES
Abstract:
(EN) The present invention is a high resolution, multi-function, conformal electronics device generally having a flexible and stretchable, high-density electrode array, integrated with a catheter (e.g., balloon catheter) for mapping, ablating, pacing and sensing of cardia tissue associated with heart arrhythmias. The active sensing electrode array can acquire diagnostic information including electrical (e.g., electrograms), mechanical (e.g., strain measurements), impedance (e.g., resistance), metabolic (e.g., pH or NADH measurement) from the underlying heart tissue surface with which it is in contact. The electrode array may be designed to be of various sizes and shapes to conform to the targeted cardiac tissue architecture (e.g. atrial, ventricle, right ventricular outflow tract, coronary sinus, pulmonary veins, etc.) corresponding to the specific type of cardiac arrhythmia. The present invention can precisely locate the source of arrhythmia as described above and deliver therapy from the same electrode array. This is achieved using a capacitive sensing electrode array that can not only monitor but also deliver electrical stimulation.
(FR) La présente invention concerne un dispositif électronique multifonction, conformé et à haute résolution comportant généralement un réseau d'électrodes à haute densité, souple et étirable, intégré à un cathéter (par exemple un cathéter à ballonnet) pour la cartographie, l'ablation, la stimulation et la détection d'un tissu cardiaque associé à des arythmies cardiaques. Le réseau d'électrodes de détection active peut acquérir des informations de diagnostic comprenant des informations électriques (par exemple des électrogrammes), mécaniques (par exemple des mesures de déformation), d'impédance (par exemple de résistance), métaboliques (par exemple mesure de pH ou de NADH) à partir de la surface du tissu cardiaque sous-jacent avec laquelle il est en contact. Le réseau d'électrodes peut revêtir diverses tailles et formes pour se conformer à la structure du tissu cardiaque cible (par exemple l'oreillette, le ventricule, le tractus de sortie du ventricule droit, le sinus coronaire, les veines pulmonaires, etc.) correspondant au type spécifique d'arythmie cardiaque. La présente invention peut localiser précisément la source d'arythmie telle que décrite ci-dessus et administrer un traitement à partir du même réseau d'électrodes. Ceci est obtenu à l'aide d'un réseau d'électrodes de détection capacitives qui peut non seulement servir pour la surveillance, mais également administrer une stimulation électrique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)