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1. (WO2018143601) PHARMACEUTICAL COMPOSITION COMPRISING SPIRULINA EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING PERIODONTAL LIGAMENT DISEASE

Pub. No.:    WO/2018/143601    International Application No.:    PCT/KR2018/001060
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Thu Jan 25 00:59:59 CET 2018
IPC: A61K 35/748
A23L 33/10
Applicants: JUNG, Woo Jae
정우재
Inventors: YANG, Seongwon
양성원
Title: PHARMACEUTICAL COMPOSITION COMPRISING SPIRULINA EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING PERIODONTAL LIGAMENT DISEASE
Abstract:
The present invention relates to a pharmaceutical composition comprising a spirulina extract as an effective ingredient for preventing or treating an oral disease. The spirulina extract induces the differentiation of periodontal ligament stem cells into periodontal ligament cells and simultaneously promotes the formation of calcium nodules. Therefore, the spirulina extract, or spirulina extract-treated periodontal ligament stem cells and periodontal ligament cells can be useful for the fixation of implants as well as the treatment of a periodontal ligament disease or the reinforcement of periodontal ligament.