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1. (WO2018143357) METHOD FOR SCREENING SUBSTANCE HAVING HIGH AFFINITY FOR TARGET SUBSTANCE

Pub. No.:    WO/2018/143357    International Application No.:    PCT/JP2018/003442
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Fri Feb 02 00:59:59 CET 2018
IPC: G01N 27/62
G01N 33/15
Applicants: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
国立大学法人浜松医科大学
Inventors: SETOU Mitsutoshi
瀬藤 光利
KONDO Takeshi
近藤 豪
Title: METHOD FOR SCREENING SUBSTANCE HAVING HIGH AFFINITY FOR TARGET SUBSTANCE
Abstract:
This method for screening a substance having a high affinity for a target substance includes: a step of preparing a measurement sample in which a sample containing a candidate substance is brought into contact with the target substance; a step in which the measurement sample is subjected to imaging mass spectrometry using matrix assisted laser desorption/ionization (MALDI) with the target substance as a matrix, to identify an ionized molecule; and a step of selecting the identified molecule as being a substance having high affinity for the target substance.