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1. (WO2018143162) COMPOUND SERVING AS PRODRUG OF HYDROXAMIC ACID OR SALT OF SAID COMPOUND, FREEZE-DRIED MEDICINAL PREPARATION, LpxC INHIBITOR, AND ANTIBACTERIAL

Pub. No.:    WO/2018/143162    International Application No.:    PCT/JP2018/002874
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Wed Jan 31 00:59:59 CET 2018
IPC: C07F 9/09
A61K 9/19
A61K 31/661
A61P 31/04
A61P 43/00
C12N 9/18
Applicants: FUJIFILM TOYAMA CHEMICAL CO., LTD.
富士フイルム富山化学株式会社
Inventors: SHOJI Muneo
庄司 宗生
NAGATO Yusuke
長遠 裕介
SUZUMURA Yuko
鈴村 祐子
Title: COMPOUND SERVING AS PRODRUG OF HYDROXAMIC ACID OR SALT OF SAID COMPOUND, FREEZE-DRIED MEDICINAL PREPARATION, LpxC INHIBITOR, AND ANTIBACTERIAL
Abstract:
The present invention addresses the problem of providing: a compound which shows potent antibacterial activity and excellent solubility in water or a salt of the compound; and a freeze-dried medicinal preparation, an LpxC inhibitor, and an antibacterial each containing the compound or salt. According to the present invention, a compound represented by general formula [1] or a salt thereof is provided. [In formula [1], R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, etc.; R3 represents a hydrogen atom, etc.; R4 represents a hydrogen atom, etc.; and n is 0 or 1.]