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1. (WO2018142322) ANTI-CCR7 ANTIBODY DRUG CONJUGATES

Pub. No.:    WO/2018/142322    International Application No.:    PCT/IB2018/050639
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Fri Feb 02 00:59:59 CET 2018
IPC: C07K 16/28
A61K 47/68
A61K 39/395
Applicants: NOVARTIS AG
Inventors: BENDER, Steven
CHARLTON, Tracy
GALKIN, Anna
GEIERSTANGER, Bernhard Hubert
GLASER, Scott Martin
KASIBHATLA, Shailaja
KNUTH, Mark
ROTTMANN, Sabine
RUE, Sarah
SPRAGGON, Glen
UNO, Tetsuo
Title: ANTI-CCR7 ANTIBODY DRUG CONJUGATES
Abstract:
This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.