Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018141975) USE OF SERUM 2-CYSTEINE PEROXIREDOXINS (2-CYS-PRDX) AS BIOMARKERS OF CHRONIC KIDNEY DISEASES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/141975 International Application No.: PCT/EP2018/052837
Publication Date: 09.08.2018 International Filing Date: 05.02.2018
IPC:
G01N 33/68 (2006.01) ,G01N 33/564 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
Applicants:
WARSZAWSKI UNIWERSYTET MEDYCZNY [PL/PL]; Żwirki i Wigury 61 02-091 Warszawa, PL
Inventors:
MUCHA, Krzysztof; PL
ZAGOŻDŻON, Radosław; PL
FORONCEWICZ, Bartosz; PL
PĄCZEK, Leszek; PL
KRATA, Natalia; PL
GALA, Kamila; PL
Agent:
ŻEBROWSKA-KUCHARZYK, Agnieszka; PL
Priority Data:
17461508.804.02.2017EP
Title (EN) USE OF SERUM 2-CYSTEINE PEROXIREDOXINS (2-CYS-PRDX) AS BIOMARKERS OF CHRONIC KIDNEY DISEASES
(FR) UTILISATION DE PEROXYRÉDOXINES 2-CYSTÉINE (2-CYS-PRDX) SÉRIQUES EN TANT QUE BIOMARQUEURS DE MALADIES RÉNALES CHRONIQUES
Abstract:
(EN) The present invention relates to the use of at least two of 2-Cys-PRDXs selected from a group consisting of PRDX1, PRDX2, PRDX3, PRDX4 and PRDX5 as a biomarker to diagnose, differentiate and/or assess the risk of chronic kidney disease (CKD). The present invention also relates to a method of diagnosis and a method of determining an increased risk of chronic kidney disease (CKD). A kit suitable for diagnosis and differentiation of chronic kidney disease (CKD) selected from the group comprising lupus nephritis (LN), IgA nephropathy (IgAN) and autosomal-dominant polycystic kidney disease (ADPKD) in a subject is also provided.
(FR) La présente invention concerne l'utilisation d'au moins deux 2-Cys-PRDX choisies dans un groupe constitué de PRDX1, PRDX2, PRDX3, PRDX4 et PRDX5 en tant que biomarqueur permettant de diagnostiquer, de différencier et/ou d'évaluer le risque de maladie rénale chronique (CKD). La présente invention concerne également un procédé de diagnostic et un procédé de détermination d'un risque accru de maladie rénale chronique (CKD). L'invention concerne également un kit approprié pour le diagnostic et la différenciation d'une maladie rénale chronique (CKD) choisie dans le groupe comprenant la néphrite lupique (LN), la néphropathie à IgA (IgAN) et la polykystose rénale autosomique dominante (ADPKD) chez un sujet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)