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1. (WO2018141938) ORAL THYROID THERAPEUTIC AGENT
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Pub. No.: WO/2018/141938 International Application No.: PCT/EP2018/052713
Publication Date: 09.08.2018 International Filing Date: 02.02.2018
IPC:
A61K 47/18 (2017.01) ,A61K 47/20 (2006.01) ,A61K 9/20 (2006.01) ,A61K 31/198 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
16
containing nitrogen
18
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
20
containing sulfur
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
197
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
198
Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
Applicants:
BERLIN-CHEMIE AG [DE/DE]; Glienicker Weg 125 12489 Berlin, DE
Inventors:
BECKER, Achim; DE
Agent:
MÜLLER & SCHUBERT PATENTANWÄLTE; Schlüterstraße 37 10629 Berlin, DE
Priority Data:
10 2017 102 192.203.02.2017DE
10 2017 122 807.129.09.2017DE
Title (EN) ORAL THYROID THERAPEUTIC AGENT
(FR) MÉDICAMENT PAR VOIE ORALE POUR LA THYROÏDE
(DE) ORALES SCHILDDRÜSENTHERAPEUTIKUM
Abstract:
(EN) The invention relates to an oral thyroid therapeutic agent, containing levothyroxine or its pharmaceutically compatible salts as active agents, in combination with at least one anti-oxidant and at least one absorption agent, wherein the weight percentage of active agents: anti-oxidants: adsorption agent is 1 : 1 : 5 - 1 : 50 : 100.
(FR) L'invention concerne un médicament par voie orale pour la thyroïde, contenant comme principe actif de la lévothyroxine ou ses sels pharmaceutiquement acceptables, en association avec au moins un agent anti-oxydant et au moins un agent adsorbant, le rapport exprimé en % en poids principe actif/anti-oxydant/adsorbant étant compris entre 1 : 1 : 5 et 1 : 50 : 100.
(DE) Beschheben wird ein orales Schilddrüsentherapeutikum, enthaltend Levothyroxin oder dessen pharmazeutisch verträgliche Salze als Wirkstoff, in Kombination mit mindestens einem Antioxidationsmittel und mindestens einem Adsorptionsmittel, wobei das Verhältnis in Gew.-% von Wirkstoff : Antioxidationsmittel : Adsorptionsmittel 1 : 1 : 5 bis 1 : 50 : 100 beträgt.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)