Search International and National Patent Collections

1. (WO2018141865) PARTICLES AND COMPOSITIONS COMPRISING THE SAME FOR TRANSFECTION

Pub. No.:    WO/2018/141865    International Application No.:    PCT/EP2018/052553
Publication Date: Fri Aug 10 01:59:59 CEST 2018 International Filing Date: Fri Feb 02 00:59:59 CET 2018
IPC: A61K 47/36
Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS
Inventors: BELBEKHOUCHE, Sabrina
PAWLAK, André
SAHALI, Djillali
CARBONNIER, Benjamin
Title: PARTICLES AND COMPOSITIONS COMPRISING THE SAME FOR TRANSFECTION
Abstract:
The present invention relates to the localized delivery of nucleic acids to cells using polyelectrolyte assemblies in the form of particles that are prepared by layer-by-layer deposition of nucleic acid and specific polycation. It also relates to compositions comprising said particles and methods for the treatment of disorders or diseases by administration of such particles.