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1. (WO2018140956) MONOVALENT ANTI-PROPERDIN ANTIBODIES AND ANTIBODY FRAGMENTS
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Pub. No.: WO/2018/140956 International Application No.: PCT/US2018/015985
Publication Date: 02.08.2018 International Filing Date: 30.01.2018
IPC:
A61K 39/395 (2006.01) ,C07K 16/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
Applicants:
ALEXION PHARMACEUTICALS, INC. [US/US]; 100 College Street New Haven, CT 06510, US
Inventors:
SHERIDAN, Douglas L.; US
TAMBURINI, Paul P.; US
MACK, Taneisha Ann-Tanara; US
VOEGTLI, Walter C.; US
Agent:
TITTEL, Jan N.; US
DECAMP, James, D.; US
Priority Data:
62/452,18730.01.2017US
Title (EN) MONOVALENT ANTI-PROPERDIN ANTIBODIES AND ANTIBODY FRAGMENTS
(FR) ANTICORPS ANTI-PROPERDINE MONOVALENTS ET FRAGMENTS D'ANTICORPS
Abstract:
(EN) Described herein are isolated monovalent antibodies or antibody fragments thereof that bind human properdin. Such antibodies are useful in methods of treatment for diseases mediated by alternative complement pathway dysregulation.
(FR) L'invention concerne des anticorps monovalents isolés ou des fragments de ces anticorps qui se lient à la properdine humaine. De tels anticorps sont utiles pour des méthodes de traitement de maladies médiées par une dysrégulation de la voie alterne du complément.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)