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1. (WO2018140519) COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE

Pub. No.:    WO/2018/140519    International Application No.:    PCT/US2018/015077
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Thu Jan 25 00:59:59 CET 2018
IPC: A61K 38/00
A61K 38/16
A61P 31/04
C07K 14/00
C07K 19/00
Applicants: FLAGSHIP PIONEERING, INC.
Inventors: MARTINEZ, Ignacio
ARMEN, Zachary, Garo
MARTIN, Barry, Andrew
AVENDANO AMADO, Maier, Steve
Title: COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE
Abstract:
Provided herein are agents, compositions, and methods for agricultural pest control, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., agricultural pest), the alteration resulting in a decrease in the fitness of the host. The invention features a composition including an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may decrease the fitness of a variety of insects that are considered agricultural pests.