Search International and National Patent Collections

1. (WO2018140478) VIRAL RESISTANT CELLS AND CULTURE SYSTEMS

Pub. No.:    WO/2018/140478    International Application No.:    PCT/US2018/015023
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Thu Jan 25 00:59:59 CET 2018
IPC: C12N 5/10
C12N 7/00
C12P 21/00
C12N 15/09
Applicants: SIGMA-ALDRICH CO. LLC
Inventors: MASCARENHAS, Joaquina
KOROKHOV, Nikolay
CHANG, Audrey
ONIONS, David
BORGSCHULTE, Trissa
GEORGE, Henry
KAYSER, Kevin
Title: VIRAL RESISTANT CELLS AND CULTURE SYSTEMS
Abstract:
Mammalian cell lines genetically engineered to be viral resistant, cell culture systems comprising agents that inhibit viral entry into or translocation within cells, and methods of using said cell lines and/or said cell culture systems to reduce or prevent viral contamination of biologic production systems.