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1. (WO2018140368) SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS

Pub. No.:    WO/2018/140368    International Application No.:    PCT/US2018/014761
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Wed Jan 24 00:59:59 CET 2018
IPC: C07D 455/00
A61K 31/4375
C07D 491/147
Applicants: MERCK SHARP & DOHME CORP.
YU, Tao
MCCAULEY, John, A.
WHITEHEAD, Alan
APGAR, James, M.
RAHEEM, Izzat, T.
DONG, Guizhen
WADDELL, Sherman, T.
LI, Hong
Inventors: YU, Tao
MCCAULEY, John, A.
WHITEHEAD, Alan
APGAR, James, M.
RAHEEM, Izzat, T.
DONG, Guizhen
WADDELL, Sherman, T.
LI, Hong
Title: SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS
Abstract:
The present invention relates to Substituted Quinolizine Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1 is as defined herein. The present invention also relates to compositions comprising at least one Substituted Quinolizine Derivative, and methods of using the Substituted Quinolizine Derivatives for treating or preventing HIV infection in a subject.