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1. (WO2018140095) METHODS FOR THE ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS

Pub. No.:    WO/2018/140095    International Application No.:    PCT/US2017/055965
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Wed Oct 11 01:59:59 CEST 2017
IPC: A61K 31/473
C07D 455/06
Applicants: O'BRIEN, Christopher, F.
Inventors: O'BRIEN, Christopher, F.
Title: METHODS FOR THE ADMINISTRATION OF CERTAIN VMAT2 INHIBITORS
Abstract:
Provided are methods of administering a vesicular monoamine transport 2 (VMAT2) inhibitor chosen from valbenazine and (+)-α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol, or a pharmaceutically acceptable salt and/or isotopic variant thereof, to a patient in need thereof wherein the patient is also being administered a strong cytochrome P450 2D6 (CYP2D6) inhibitor.