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1. (WO2018139825) IMIDAZOPYRIDAZINE COMPOUND
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Pub. No.: WO/2018/139825 International Application No.: PCT/KR2018/000982
Publication Date: 02.08.2018 International Filing Date: 23.01.2018
IPC:
C07D 487/22 (2006.01) ,A61K 31/5025 (2006.01) ,A61K 31/519 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
22
in which the condensed system contains four or more hetero rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50
Pyridazines; Hydrogenated pyridazines
5025
ortho- or peri-condensed with heterocyclic ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
Applicants:
한미약품 주식회사 HANMI PHARMACEUTICAL CO., LTD. [KR/KR]; 경기도 화성시 팔탄면 무하로 214 214, Muha-ro, Paltan-myeon Hwaseong-si, Gyeonggi-do 18536, KR
Inventors:
함영진 HAM, Young Jin; KR
강석종 KANG, Seok Jong; KR
Agent:
특허법인 정안 HONESTY & JR PARTNERS INTELLECTUAL PROPERTY LAW GROUP; 서울시 강남구 선릉로 615, 5층 5F, 615 Sunreung-ro, Gangnam-gu, Seoul 06103, KR
Priority Data:
10-2017-001276726.01.2017KR
Title (EN) IMIDAZOPYRIDAZINE COMPOUND
(FR) COMPOSÉ D'IMIDAZOPYRIDAZINE
(KO) 이미다조피리다진 화합물
Abstract:
(EN) The present invention relates to an imidazopyridazine compound having cell growth inhibitory activity and a pharmaceutical composition comprising the imidazopyridazine compound for preventing or treating cancer or a tumor. The imidazopyridazine compound of chemical formula 1 according to the present invention has excellent cell growth inhibitory activity, and thus can be favorably used as a preventive or therapeutic agent for cancer or a tumor.
(FR) La présente invention concerne un composé d'imidazopyridazine présentant une activité inhibitrice de la croissance cellulaire et une composition pharmaceutique comprenant le composé d'imidazopyridazine pour la prévention ou le traitement du cancer ou d'une tumeur. Le composé d'imidazopyridazine de formule chimique 1 selon la présente invention présente une excellente activité inhibitrice de la croissance cellulaire, et peut donc être avantageusement utilisé en tant qu'agent préventif ou thérapeutique du cancer ou d'une tumeur.
(KO) 본 발명은 세포 성장 억제 활성을 갖는 이미다조피리다진 화합물 및 이를 포함하는 암 또는 종양의 예방 또는 치료용 약학적 조성물에 관한 것으로서, 본 발명에 따른 화학식 1의 이미다조피리다진 화합물은 세포 성장 억제 활성이 우수하므로, 암 또는 종양의 예방 또는 치료제로서 유용하게 사용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)