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1. (WO2018139626) SOLID PREPARATION COMPRISING QUINAZOLINE DERIVATIVE

Pub. No.:    WO/2018/139626    International Application No.:    PCT/JP2018/002626
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Tue Jan 30 00:59:59 CET 2018
IPC: A61K 31/5377
A61K 9/20
A61K 47/02
A61K 47/04
A61K 47/38
A61P 35/00
A61P 43/00
Applicants: SHIONOGI & CO., LTD.
塩野義製薬株式会社
Inventors: YOKOYAMA Reiji
横山 怜示
SAKUMA Satoshi
佐久間 聡
AIKAWA Shohei
相川 昇平
TANAKA Hironori
田中 宏典
Title: SOLID PREPARATION COMPRISING QUINAZOLINE DERIVATIVE
Abstract:
Provided is a preparation which is obtained by coating a preparation, said preparation comprising a compound represented by formula (I), a salt thereof or crystals of the same, with a light stabilizer and a polymer, in particular, one or more members selected from among titanium oxide, yellow iron sesquioxide and talc as the light stabilizer and hydroxypropylmethylcellulose as the polymer. Owing to this structure, the obtained preparation shows little increase in analogues and is hardly colored even upon light irradiation.