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1. WO2018139624 - COMPOSITION FOR PROMOTING INSULIN SECRETION

Publication Number WO/2018/139624
Publication Date 02.08.2018
International Application No. PCT/JP2018/002614
International Filing Date 29.01.2018
IPC
A61K 38/01 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
01Hydrolysed proteins; Derivatives thereof
A61K 35/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
20Milk; Whey; Colostrum
A61P 3/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
CPC
A61K 35/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
20Milk; Whey; Colostrum
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
01Hydrolysed proteins; Derivatives thereof
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
Applicants
  • 株式会社明治 MEIJI CO., LTD. [JP]/[JP]
Inventors
  • 高井 祥子 TAKAI Shoko
  • 中山 恭祐 NAKAYAMA Kyosuke
  • 三本木 千秋 SANBONGI Chiaki
Agents
  • 横田 修孝 YOKOTA Nobutaka
  • 榎 保孝 ENOKI Yasutaka
  • 大森 未知子 OMORI Michiko
Priority Data
2017-01404730.01.2017JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) COMPOSITION FOR PROMOTING INSULIN SECRETION
(FR) COMPOSITION POUR FAVORISER LA SÉCRÉTION D'INSULINE
(JA) インスリン分泌促進用組成物
Abstract
(EN)
The purpose of the present invention is to provide a novel composition for promoting insulin secretion. According to the present invention, provided is a composition for promoting insulin secretion, said composition comprising a whey protein hydrolysate as an active ingredient, wherein the whey protein hydrolysate contains a dipeptide and the dipeptide is at least one member selected from the group consisting of Ile-Leu, Leu-Ala, Ala-Leu, Val-Leu, Lys-Ile, Leu-Leu, Ile-Asn, Leu-Glu, Leu-Val, Ile-Val, Ile-Ile and Leu-Ile.
(FR)
L'objet de la présente invention est de fournir une nouvelle composition pour favoriser la sécrétion d'insuline. Selon la présente invention, l'invention concerne une composition pour favoriser la sécrétion d'insuline, ladite composition comprenant un hydrolysat de protéines lactosériques en tant que principe actif, l'hydrolysat de protéines lactosériques contenant un dipeptide et le dipeptide étant au moins un élément choisi dans le groupe constitué par Ile-Leu, Leu-Ala, Ala-Leu, Val-Leu, Lys-Ile, Leu-Leu, Ile-Asn, Leu-Glu, Leu-Val, Ile-Val, Ile-Ile et Leu-Ile.
(JA)
本発明は、新規なインスリン分泌促進用組成物の提供を目的とする。本発明によれば、ホエイタンパク質加水分解物を有効成分として含んでなるインスリン分泌促進用組成物であって、ホエイタンパク質加水分解物がジペプチドを含み、前記ジペプチドが、Ile-Leu、Leu-Ala、Ala-Leu、Val-Leu、Lys-Ile、Leu-Leu、Ile-Asn、Leu-Glu、Leu-Val、Ile-Val、Ile-Ile及びLeu-Ileからなる群から選択される1種又は2種以上である組成物が提供される。
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