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1. (WO2018139415) ENDOTOXIN ADSORBENT
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Pub. No.: WO/2018/139415 International Application No.: PCT/JP2018/001838
Publication Date: 02.08.2018 International Filing Date: 22.01.2018
IPC:
B01J 20/22 (2006.01) ,A23P 30/00 (2016.01) ,G01N 30/02 (2006.01) ,G01N 30/88 (2006.01) ,A61K 47/36 (2006.01) ,A61K 47/42 (2017.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
20
Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
22
comprising organic material
[IPC code unknown for A23P 30]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
88
Integrated analysis systems specially adapted therefor, not covered by a single one of groups G01N30/04-G01N30/86146
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
Applicants:
ナガセケムテックス株式会社 NAGASE CHEMTEX CORPORATION [JP/JP]; 大阪府大阪市西区新町1丁目1番17号 1-17, Shinmachi 1-chome, Nishi-ku, Osaka-shi Osaka 5508668, JP
Inventors:
中村 大輔 NAKAMURA Daisuke; JP
前田 祐希 MAEDA Yuki; JP
Agent:
多田 央子 TADA Eiko; JP
神野 直美 JINNO Naoyoshi; JP
上代 哲司 JODAI Tetsuji; JP
Priority Data:
2017-01096625.01.2017JP
Title (EN) ENDOTOXIN ADSORBENT
(FR) ABSORBANT D'ENDOTOXINE
(JA) エンドトキシン吸着剤
Abstract:
(EN) An endotoxin adsorbent, said endotoxin adsorbent comprising crystalline cellulose having a nitrogen atom-containing cationic group, can sufficiently remove endotoxins from a material, from which the endotoxins are to be removed, containing a substance having a cationic group. Also, the endotoxin adsorbent can efficiently remove endotoxins from a highly viscous material. In a typical case, the nitrogen atom-containing cationic group may be a functional group derived from a polyvalent amine and/or a quaternary ammonium salt. In the crystalline cellulose having the nitrogen atom-containing cationic group, the content of the nitrogen atom-containing cationic group may be 0.05-3 meq/dry.g in terms of anion exchange capacity.
(FR) Un adsorbant d'endotoxine, ledit adsorbant d'endotoxine comprenant de la cellulose cristalline ayant un groupe cationique contenant un atome d'azote, peut éliminer suffisamment des endotoxines d'un matériau, à partir duquel les endotoxines doivent être éliminées, contenant une substance ayant un groupe cationique. De plus, l'adsorbant d'endotoxine peut éliminer efficacement des endotoxines d'un matériau hautement visqueux. Dans un cas typique, le groupe cationique contenant un atome d'azote peut être un groupe fonctionnel dérivé d'une amine polyvalente et/ou d'un sel d'ammonium quaternaire. Dans la cellulose cristalline ayant le groupe cationique contenant un atome d'azote, la teneur du groupe cationique contenant un atome d'azote peut être de 0.05-3 meq/dry.g en termes de capacité d'échange d'anions.
(JA) 窒素原子を含むカチオン性基を有する結晶セルロースを備えるエンドトキシン吸着剤は、カチオン性基を有する物質を含むエンドトキシン除去対象材料から十分にエンドトキシンを除去することができ、また、粘性の高い材料からも効率よくエンドトキシンを除去することができる。窒素原子を含むカチオン性基は、代表的には多価アミンに由来する官能基、及び/又は第4級アンモニウム塩とすることができる。窒素原子を含むカチオン性基を有する結晶セルロースにおける、窒素原子を含むカチオン性基の含有量は、陰イオン交換容量として、0.05~3meq/dry・gとすることができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)