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1. (WO2018138607) COMPOSITIONS COMPRISING ANTI-FEL D1 ANTIBODIES AND METHODS FOR REDUCING AT LEAST ONE SYMPTOM OF HUMAN ALLERGY TO CATS
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Pub. No.: WO/2018/138607 International Application No.: PCT/IB2018/050320
Publication Date: 02.08.2018 International Filing Date: 18.01.2018
IPC:
A61K 39/395 (2006.01) ,A61K 9/00 (2006.01) ,A61K 47/42 (2017.01) ,C07K 16/18 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
Applicants:
NESTEC SA [CH/CH]; Avenue Nestle 55 1800 Vevey, CH
Inventors:
WOOSTER, Timothy James; CH
SATYARAJ, Ebenezer; US
GERBER, Beat; CH
GOMBAS, Eddy; CH
Priority Data:
62/449,88324.01.2017US
Title (EN) COMPOSITIONS COMPRISING ANTI-FEL D1 ANTIBODIES AND METHODS FOR REDUCING AT LEAST ONE SYMPTOM OF HUMAN ALLERGY TO CATS
(FR) COMPOSITIONS COMPRENANT DES ANTICORPS ANTI-FEL D1 ET PROCÉDÉS DE RÉDUCTION D'AU MOINS UN SYMPTÔME D'ALLERGIE HUMAINE AUX CHATS
Abstract:
(EN) Compositions and methods reduce symptoms of human allergy to cats. The effectiveness of a molecule which specifically binds to Feline domesticus allergen number 1 (Fel Dl) is enhanced by prolonging the time the immunoglobulin stays within the mouth of a cat to whom the anti-Fel Dl molecule is administered in a pet food. The compositions and methods use a powder that is a dried hydrogel encapsulating the anti-Fel Dl molecule, and the hydrogel is based on gelatin, collagen peptides, or gelatin and collagen peptides; and carrageenan. The methods of making the powder provide a high encapsulation efficacy, sustained release of the anti-Fel Dl molecule in the cat's mouth, and oral adhesion of the anti-Fel Dl molecule in the cat's mouth.
(FR) L’invention concerne des compositions et des procédés pour réduire les symptômes de l'allergie humaine aux chats. L'efficacité d'une molécule qui se lie spécifiquement au numéro 1 d'allergène de Felis domesticus (Fel Dl) est améliorée en prolongeant le temps que l'immunoglobuline reste à l'intérieur de la bouche d'un chat auquel la molécule anti-Fel Dl est administrée dans un aliment pour animaux de compagnie. Les compositions et les procédés utilisent une poudre qui est un hydrogel séché encapsulant la molécule anti-Fel Dl, et l'hydrogel est à base de gélatine, de peptides de collagène ou de gélatine et de peptides de collagène ; et de carraghénane. Les procédés de fabrication de la poudre fournissent une efficacité d'encapsulation élevée, une libération prolongée de la molécule anti-Fel Dl dans la bouche du chat, et une adhérence buccale de la molécule anti-Fel Dl dans la bouche du chat.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)