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1. (WO2018138354) RORGAMMA MODULATORS AND USES THEREOF

Pub. No.:    WO/2018/138354    International Application No.:    PCT/EP2018/052161
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Tue Jan 30 00:59:59 CET 2018
IPC: C07D 295/185
C07D 405/12
C07D 295/155
A61K 31/496
A61K 31/4427
A61P 37/02
A61P 29/00
A61P 3/00
Applicants: GENFIT
Inventors: DELHOMEL, Jean-François
PERSPICACE, Enrico
MAJD, Zouher
PARROCHE, Peggy
WALCZAK, Robert
BONNET, Pascal
FOGHA, Jade
Title: RORGAMMA MODULATORS AND USES THEREOF
Abstract:
The present invention provides novel compounds of formula (la) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, metabolic diseases, fibrotic diseases, or cholestatic diseases. (formula Ia)