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1. (WO2018138274) ELUXADOLINE CRYSTALLINE FORMS AND PROCESSES FOR THEIR PREPARATION
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Pub. No.: WO/2018/138274 International Application No.: PCT/EP2018/051975
Publication Date: 02.08.2018 International Filing Date: 26.01.2018
IPC:
C07D 233/64 (2006.01) ,A61K 31/4164 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
233
Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
54
having two double bonds between ring members or between ring members and non-ring members
64
with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
Applicants:
QUIMICA SINTETICA, S. A. [ES/ES]; Gran Via Carles III, 98, 7è. Edifici Trade 08028 BARCELONA, ES
Inventors:
BARRECA, Giuseppe; IT
VENTIMIGLIA, Giampiero; IT
MASCIOCCHI, Norberto; IT
Agent:
OFICINA PONTI, S.L.P.; C. Consell de Cent, 322 08007 BARCELONA, ES
Priority Data:
17382038.227.01.2017EP
17382833.604.12.2017EP
Title (EN) ELUXADOLINE CRYSTALLINE FORMS AND PROCESSES FOR THEIR PREPARATION
(FR) FORMES CRISTALLINES D'ÉLUXADOLINE ET LEURS PROCÉDÉS DE PRÉPARATION
Abstract:
(EN) Novel crystalline forms of Eluxadoline, having the formula (I), are described. Also described are the processes for the preparation of said crystalline forms.
(FR) La présente invention concerne de nouvelles formes cristallines d'Éluxadoline, répondant à la formule (I). L'invention concerne aussi les procédés de préparation desdites formes cristallines.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)