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1. (WO2018138005) PIPETTING DEVICE FOR PULSED PIPETTING WITH A PIPETTING PISTON MOVEMENT REGULATED ON THE BASIS OF A DETERMINATION OF THE WORKING GAS PRESSURE

Pub. No.:    WO/2018/138005    International Application No.:    PCT/EP2018/051303
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Sat Jan 20 00:59:59 CET 2018
IPC: B01L 3/02
Applicants: HAMILTON BONADUZ AG
Inventors: ROMER, Hanspeter
ETTINGER, Reto
GYSEL, Fridolin
RAST, Jürg
HILTI, Jonas
Title: PIPETTING DEVICE FOR PULSED PIPETTING WITH A PIPETTING PISTON MOVEMENT REGULATED ON THE BASIS OF A DETERMINATION OF THE WORKING GAS PRESSURE
Abstract:
The invention relates to pipetting device (10) for the pulsed pipetting of dosing liquids in small dose volumes of less than 2 μΙ, wherein the pipetting device (10) comprises: a pipetting channel (11) at least partially filled with working gas (34), a pipetting tip (26), which is accessible through a pipetting opening (30), such that the volume of dosing liquid drawn into the receiving chamber through the pipetting opening (30) can be varied by means of a change in the pressure of the working gas in the receiving chamber, a pipetting piston (14) for changing the pressure of the working gas (34) and accommodated in the pipetting channel so as to be capable of movement along the pipetting channel (11), a motion drive (20) to drive the pipetting piston (14) for movement along the pipetting channel (11), a control device (24) for controlling the motion drive (20), and a pressure sensor (38) for determining the pressure of the working gas, wherein the control device (24) is designed to control the motion drive (20) in order to generate a pressure pulse in the pipetting channel (11) with a pulse duration of no longer than 40 ms on the basis of the pressure signal output by the pressure sensor (38) in such a manner that the pressure of the working gas (34) during the pulse follows a predefined working gas target pressure pulse characteristic.