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1. (WO2018137748) ANTIVIRAL, ANTIFIBROTIC AND ANTICANCER ACTIVITIES OF ROYAL-JELLY PROTEINS

Pub. No.:    WO/2018/137748    International Application No.:    PCT/EG2017/000022
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Tue Aug 08 01:59:59 CEST 2017
IPC: A61K 35/64
A61K 35/644
A61K 38/08
A61K 38/16
A61K 38/17
A23L 1/305
A61P 3/06
A61P 31/02
A61P 31/12
Applicants: EL-FIKY, Salem
ABU-SARIE, Marwa
HABASHY, Noha
Inventors: EL-FIKY, Salem
ABU-SARIE, Marwa
HABASHY, Noha
Title: ANTIVIRAL, ANTIFIBROTIC AND ANTICANCER ACTIVITIES OF ROYAL-JELLY PROTEINS
Abstract:
This invention discloses purified proteins from Apis mellifera royal jelly (RJ) named major RJ protein 2 and its isoform X1 have proven potent efficacy against HCV and HBV and their complications in the liver "fibrosis and cancer". Methods for the effective RJ proteins purification, identification, safety and examination against HCV, HBV, fibrosis, and HepG-2 cell line are disclosed. The comparisons with the current most potent anti-HCV drug "Sovaldi" are also disclosed.