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1. (WO2018137627) SUSTAINED RELEASE COMPOSITION OF ARIPIPRAZOLE AND DERIVATIVE THEREOF AND PREPARATION METHOD FOR SAME

Pub. No.:    WO/2018/137627    International Application No.:    PCT/CN2018/073897
Publication Date: Fri Aug 03 01:59:59 CEST 2018 International Filing Date: Thu Jan 25 00:59:59 CET 2018
IPC: A61K 9/16
A61K 9/54
A61K 31/496
A61K 47/34
A61P 25/18
Applicants: AC PHARMACEUTICALS CO., LTD.
广州帝奇医药技术有限公司
Inventors: LIU, Feng
刘锋
LAI, Shuting
赖树挺
CAO, Fuchun
曹付春
ZHENG, Yang
郑阳
LIAN, Yuanfa
连远发
Title: SUSTAINED RELEASE COMPOSITION OF ARIPIPRAZOLE AND DERIVATIVE THEREOF AND PREPARATION METHOD FOR SAME
Abstract:
Disclosed are a sustained release composition of aripiprazole and a derivative thereof and a preparation method therefor. The non-solvent preparation raw materials of the sustained release composition comprise aripiprazole and a sparingly water-soluble polymer. The sustained-release composition has a good release performance, has no obvious release delay period or burst release phenomenon, and can maintain a stable blood drug concentration for several weeks or more, and has a relatively good stability.