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1. WO2018137428 - HIGH EFFICIENCY CULTURING SYSTEM FOR LARGE-SCALE CELL PRODUCTION AND CULTURING, AND APPLICATION METHOD

Publication Number WO/2018/137428
Publication Date 02.08.2018
International Application No. PCT/CN2017/115779
International Filing Date 13.12.2017
Chapter 2 Demand Filed 22.05.2018
IPC
C12M 3/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
CPC
C12M 23/14
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
02Form or structure of the vessel
14Bags
C12M 29/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
29Means for introduction, extraction or recirculation of materials, e.g. pumps
Applicants
  • 国健呈诺生物科技(北京)有限公司 NATIONAL HEALTH ASSOCIATED ALLIFE BIOLOGICAL SCIENCE AND TECHNOLOGY (BEIJING) CO., LTD. [CN]/[CN]
Inventors
  • 顾雨春 GU, Yuchun
  • 刘建强 LIU, Jianqiang
Agents
  • 北京轻创知识产权代理有限公司 KEYCOM PARTNERS, P.C.
Priority Data
201710419018.906.06.2017CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) HIGH EFFICIENCY CULTURING SYSTEM FOR LARGE-SCALE CELL PRODUCTION AND CULTURING, AND APPLICATION METHOD
(FR) SYSTÈME DE CULTURE À HAUT RENDEMENT POUR LA PRODUCTION ET LA CULTURE DE CELLULES À GRANDE ÉCHELLE, ET PROCÉDÉ D'APPLICATION
(ZH) 一种大规模细胞生产和培养的高效率培养系统及应用方法
Abstract
(EN) A high efficiency culturing system for large-scale cell production and culturing, and an application method. The system comprises at least one cell culture bag and at least one cell culture medium storage bag, the cell culture bag being used for cell culturing, the cell culture medium storage bag being used for storing a prepared cell culture medium which is infused for the cell culturing of the cell culture bag. The cell culture bag and the cell culture medium storage bag have different specifications, the bags are usually independent, and a sterile heat-seal tube connection machine is used when cell culture medium infusion is performed to ensure that heat-seal connection and disconnection are performed in a sterile state.
(FR) L'invention concerne un système de culture à haut rendement pour la production et la culture de cellules à grande échelle, et un procédé d'application. Le système comprend au moins un sac de culture cellulaire et au moins un sac de stockage de milieu de culture cellulaire, le sac de culture cellulaire étant utilisé pour la culture cellulaire, le sac de stockage de milieu de culture cellulaire étant utilisé pour stocker un milieu de culture cellulaire préparé qui est injecté pour la culture cellulaire dans le sac de culture cellulaire. Le sac de culture cellulaire et le sac de stockage de milieu de culture cellulaire ont des spécifications différentes; ces sacs sont habituellement indépendants l'un de l'autre, et une machine de raccordement de tube par thermoscellage stérile est utilisée lorsque le milieu de culture cellulaire est injecté afin de garantir que le raccordement et le détachement soient effectués à l'état stérile.
(ZH) 一种大规模细胞生产和培养的高效率培养系统及应用方法,包括至少一个细胞培养袋和至少一个细胞培养基保存袋;所述细胞培养袋用于细胞培养,所述细胞培养基保存袋用于储存制备的细胞培养基,为细胞培养袋的细胞培养输注细胞培养基,细胞培养袋和细胞培养基保存袋均存在不同的规格,各个袋体之间平时为独立状态,需要进行细胞培养基输注时采用无菌热合接管机保证无菌状态下进行热合连接、断开。
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