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1. (WO2018137400) APPLICATION OF CYSTATINS IN PREPARATION OF DRUG FOR TREATING OR PREVENTING ULTRAVIOLET LIGHT-INDUCED SKIN DAMAGE
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Pub. No.: WO/2018/137400 International Application No.: PCT/CN2017/113636
Publication Date: 02.08.2018 International Filing Date: 29.11.2017
IPC:
A61K 38/55 (2006.01) ,A61P 17/16 (2006.01) ,A23L 33/00 (2016.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
16
Emollients or protectives, e.g. against radiation
[IPC code unknown for A23L 33]
Applicants:
上海交通大学 SHANGHAI JIAO TONG UNIVERSITY [CN/CN]; 中国上海市 闵行区东川路800号 800 Dong Chuan Rd, Minhang District Shanghai 200240, CN
Inventors:
殷卫海 YIN, Weihai; CN
张铭超 ZHANG, Mingchao; CN
Agent:
北京安杰律师事务所 ANJIE LAW FIRM; 中国北京市 朝阳区东方东路19号亮马桥外交办公大楼D1座19层 19/F, Tower D1 Liangmaqiao Diplomatic Office Building No.19 Dongfangdonglu, Chaoyang District Beijing 100600, CN
Priority Data:
201710061509.026.01.2017CN
Title (EN) APPLICATION OF CYSTATINS IN PREPARATION OF DRUG FOR TREATING OR PREVENTING ULTRAVIOLET LIGHT-INDUCED SKIN DAMAGE
(FR) APPLICATION DE CYSTATINES DANS LA PRÉPARATION DE MÉDICAMENT DESTINÉ AU TRAITEMENT OU À LA PRÉVENTION DE LÉSIONS CUTANÉES INDUITES PAR LA LUMIÈRE ULTRAVIOLETTE
(ZH) 胱氨酸蛋白酶抑制剂在制备治疗或预防紫外光诱导的皮肤损伤药物中的应用
Abstract:
(EN) An application of cystatins in preparation of a drug for treating or preventing ultraviolet light-induced skin damage. The cystatins comprise a cystatin and a cysteine protease inhibitor which can inhibit the cysteine protease activity and can significantly reduce ultraviolet light-induced skin damage, such as cell death and tissue damage.
(FR) La présente invention concerne une application de cystatines dans la préparation d'un médicament destiné au traitement ou à la prévention de lésions cutanées induites par la lumière ultraviolette. Les cystatines comprennent une cystatine et un inhibiteur de cystéine protéase qui peuvent inhiber l'activité de la cystéine protéase et peuvent réduire de manière significative les lésions cutanées induites par la lumière ultraviolette, telles que la mort cellulaire et les lésions tissulaires.
(ZH) 胱氨酸蛋白酶抑制剂在制备防治紫外光诱导的皮肤损伤药物中的应用。其中,胱氨酸蛋白酶抑制剂,包括可以抑制半胱氨酸蛋白酶活力的胱氨酸蛋白酶抑制剂和半胱氨酸蛋白酶抑制剂均可以显著减少紫外光诱导的皮肤损伤,例如细胞死亡和组织损伤。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)