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1. (WO2018136845) MEDICAL PRODUCTS AND METHODS CONFIGURED FOR CONTROLLED RELEASE OF NITROUS OXIDE

Pub. No.:    WO/2018/136845    International Application No.:    PCT/US2018/014599
Publication Date: Fri Jul 27 01:59:59 CEST 2018 International Filing Date: Mon Jan 22 00:59:59 CET 2018
IPC: A61M 25/00
A61F 13/00
A61L 15/20
A61L 15/44
A61L 15/22
A61L 26/16
Applicants: BIOCREDE INC.
Inventors: CHEN, Hao
RENEHAN, Kevin
HO, Kwun Yin
WOLF, Alexander
Title: MEDICAL PRODUCTS AND METHODS CONFIGURED FOR CONTROLLED RELEASE OF NITROUS OXIDE
Abstract:
The disclosure concerns various medical devices implemented to provide a nitric oxide rich environment for anti-microbial or anti-thrombogenic benefits. The medical device generally includes a nitric oxide donor material that is contained within a sealed cavity, and a transport medium that defines and captivates the entirety of the cavity, wherein the transport medium is permeable to both water and nitric oxide. As the nitric oxide donor material becomes saturated with water from the surrounding tissue or fluids, nitric oxide is chemically released, and the resulting nitric oxide is communicated through the transport medium to a treatment site for anti-microbial and anti-thrombogenic benefits.